We are powerless when we are faced with the impossible-to-predict future.
We are helpless when it comes to dealing with the future that is impossible to predict.
ご質問ありがとうございます。
① "We are powerless"=「私たちは無力である」
"when we are faced with the impossible-to-predict future."=「予測不可能な未来に対して。」
② "We are helpless"=「私たちは無力だ」
"when it comes to dealing with the future that is impossible to predict."=「予測不可能な未来と対決するときは。」
ご参考になると幸いです。