People's sensitivity to temperature varies depending on the person, so it's difficult to know how high or low you should set the temperature on your air conditioning.
この場合、次のような言い方ができますよ。
ーPeople's sensitivity to temperature varies depending on the person, so it's difficult to know how high or low you should set the temperature on your air conditioning.
「人の体感温度は人それぞれだから、空調の温度調整をどのくらい高くするか低くするか知るのが難しい」
ここの「体感温度」は sensitivity to temperature のように言うと良いでしょう。
ご参考まで!