There's something different about you. Did you part your hair differently?
You look different. Did you part your hair on the other side?
この場合、次のような言い方ができますよ。
ーThere's something different about you. Did you part your hair differently?
「何か違うね。分け目変えた?」
to part one's hair で「髪を分ける」
ーYou look different. Did you part your hair on the other side?
「いつもと違うね。反対側に髪分けてる?」
on the other side で「反対側に」
ご参考まで!