「どうゆう状態で在りたいか」= How do you want to live? / Is this how you want to live? / Is the state in which you want to live? / What do you want from your life?
落ち込んでいる人にアドバイスをしたいなら、こういう表現を使えば良いと思います:
The important thing is to decide what you want from your life.
(大事なのは、どうゆう状態で在るかだよ)
It is important to think about what you want to change in your life.
(自分の人生に何を変えたいのか?それを考える事が大事だよ。)