I have so much homework during school break that I don't think I can finish it.
「休校中の宿題が多すぎて終わりそうにない」は"I have so much homework during school break that I don't think I can finish it."と言えます。
単語:
「多すぎて」は"Too much/many"と言う意味です。
「宿題」は"Homework"と言う意味です。
「休校」は"School break"か"School vacation"と言えます。
ご参考になれば幸いです。