One single controversial remark can engender feelings of ill will between people.
One stupid comment can cause hard feelings between two people.
ーOne single controversial remark can engender feelings of ill will between people.
「たった一つの問題発言が人の間に敵対心を生むことがある」
to engender feelings of ill will で「敵対心を生む」と言えます。
ーOne stupid comment can cause hard feelings between two people.
「愚かなコメントが２人の間に悪感情を引き起こすことがある」
to cause hard feelings「悪感情を引き起こす」を使っても言えますよ。
ご参考まで！
カナダ 
