回答
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"As we get older, our skin gets harder and the skin lotion doesn't get in"
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"As we age, our skin gets tougher and skin lotion isn't as effective."
"skin sclerosis" それとも "scleroderma" は 「強皮症」なのでこの文章で使えませんと思います。代わりに "harder" や "tougher" は適切です。
"As we get older, our skin gets harder and the lotion doesn't get in"
"as we get older" 「年を取ると」
"our skin gets harder" 「皮膚が固くなり」
"skin" 「皮膚」
"gets harder" 「固くなり」
"the skin lotion doesn't get in" 「化粧水が入らなくなる」
"skin lotion" 「化粧水」
"As we age, our skin gets tougher and skin lotion isn't as effective."
"as we age" 「年を取ると」
"gets tougher" 「固くなり」
"isn't as effective" 「効かなくなる」