Don't tell him/her something irresponsible to fool him/her.
Don't tell him/her something irresponsible if you are not serious.
Don't tell him/her something irresponsible unless you mean it.
「相手を惑わすような無責任なことは言わないで!」は、
Don't tell him/her something irresponsible to fool him/her.
Don't tell him/her something irresponsible if you are not serious.
Don't tell him/her something irresponsible unless you mean it.
などが伝わりやすいと思います。
※irresponsible 無責任な
※fool 惑わす
※serious 本気の
※mean ~するつもりである
※unless you mean it 本気でないなら