They live at a place that is 30 minutes away from my house by train.
Where they live takes about 30 minutes to my house by train.
They live at a place = 彼らは住んでいる場所
30 minutes from my house by train = 私の家から電車で30分
Where they live = 彼らが住んでいる場所は
Takes = かかる
about = くらい、ほど
To my house by train = 電車で私の家まで
In order to sound the most natural, it is unnecessary to translate every word.
For example, you don't need to make the sentence long:
They live in a house that is in a place that is 30 minutes from my house by train.