What A said and what B said are completely different.
There's a world of difference between what A and B said.
この場合、次のような言い方ができますよ。
ーWhat A said and what B said are completely different.
「Aが言ったこととBが言ったことは完全に異なる」=「全然ちがう」
ーThere's a world of difference between what A and B said.
「AとBが言ったことの間には天と地の差がある」=「全然違う」
ご参考まで!