"何をやらせても不器用"
何をやらせても = no matter what they do
不器用 = awkward
No matter what they do, they are awkward.
They are awkward no matter what they do.
例文:
チャーリーブラウンは、何をやらせても不器用だ。
Charlie Brown is awkward no matter what he does.
No matter what he does, Charlie Brown is awkward.
あの人は、何をやらせても不器用だ。
No matter what s/he does, s/he is awkward.
S/he's awkward no matter what s/he does.