It's quite a distance from the train station to the shopping district, so you'll need a car.
この場合、次のような言い方ができますよ。
ーIt's quite a distance from the train station to the shopping district, so you'll need a car.
「駅と繁華街はかなり離れているので、車が必要になりますよ」
It's quite a distance from A to B で「AとBは結構離れている」と言えます。
ご参考まで!