目的地は「destination」、最寄り駅は一番近い駅という意味ので英語にすると「closest station」になります。
日本で道案内の時にこの2つの言葉はすごく大事です。もっと簡単にいう、「The closest station is ○○」。上野動物園について教えているので、「to the destination」は言わなくてもいいです。
The Ueno Station is the closest stop to the Ueno Zoo.
The ______ Station is closest to your/our destination.
The Ueno Station is the closest stop to the Ueno Zoo.
If you know the names of the locations you can explain which station is nearest to the destination the person wants to visit.
Closest - the nearest or easiest to get to (Tom was the closest to the phone when it rang)
Stop - station, or terminal (Which stop do I need to get off at?)
You could also say,
The ______ Station is closest to your/our destination.
Destionation, where you want to go for shopping, siteseeing, etc. (The Skytree is our final destionation.)
The Ueno Station is the closest stop to the Ueno Zoo.（上野動物園の最寄りの駅は上野駅です）
場所の名前を知っていれば、最寄りの駅がどこか説明できます。
Closest - 最も近い、最も行きやすい
Tom was the closest to the phone when it rang
（電話が鳴ったとき受話器に一番近かったのはトムでした）
Stop - 駅またはターミナル
Which stop do I need to get off at?（どこの駅で降りればいいですか）
次のように言うこともできます。
The ______ Station is closest to your/our destination.（あなた／私たちの目的地に最も近いのは______駅です。）
Destionation - 買い物・観光などをしに行く場所
The Skytree is our final destionation.（私たちの最終目的地はスカイツリーです）
The closest train station to Ueno Zoo is Ueno station
Ueno train station is close to Ueno Zoo
When you want to explain that the closest train station to Ueno Zoo is Ueno train station; then you may explain in the following ways:
-The closest train station to Ueno Zoo is Ueno station
-Ueno train station is close to Ueno Zoo
上野動物園の最寄りの駅は上野駅であると説明したいなら、次のように言えます。
-The closest train station to Ueno Zoo is Ueno station（上野動物園の最寄りの駅は上野駅です）
-Ueno train station is close to Ueno Zoo（上野駅は上野動物園に近いです）
The word "closest" is a superlative so it is necessary to use "the" before hand. Since Ueno Zoo is a specific place, you also need to use "the" beforehand. I hope that this helps. :)
This is directly telling the person that the nearest station to the zoo.
There are other words that you could use for nearest. You could say:
the most convenient
immediate
Saying "in the ball park" is telling the person that there is a station nearby. You could use this when you are not sure about where a station is or if you are not sure if it is the closest one.
これは、動物園の最寄りの駅がどこかを単刀直入に伝えます。
"nearest" の代わりに次の語句も使えます。
the most convenient（最も便のいい）
immediate（接近した）
"in the ball park" でも駅が近くにあることを表せます。
これは、駅の場所がはっきり分からないときや、あるいはそれが最寄りの駅であるか分からないときに使うことができます。
When explaining directions, you want to explain where the nearest train station of the destination is. You want to explain this? For example, when you want to explain that Ueno Station is the closest station to Ueno Zoo.
The station nearest to the Ueno Zoo is the Ueno station.
The station nearest to the Ueno Zoo is the Ueno station refers to the surrounding stations and how the distance of the Ueno station is the closest one.
The station nearest to the Ueno Zoo is the Ueno station（上野動物園の最寄りの駅は上野駅です）
は、「上野駅が最寄り駅である」と伝えています。
The most accessible stop to your destination is the Ueno stop
When you reach the Ueno stop you will be within walking distance of your destination
When we say "accessible" we are mentioning that there are no obstacles or major roads blocking our destination, as it is reachable without obstruction.
"Walking distance" means that is is possible to get to your intended destination by foot. You do not need to take more forms of transport to get where you want to go.
For example "Wheelchair accessible" means that a wheelchair can enter and leave a place without problems
アメリカ合衆国 
南アフリカ 
イギリス 
アイルランド 
